This class is not about biology. It is about teaching yourself to think like a Mowshowitz. As a high school student I taught myself more conceptual material in AP than I ever garnered in C2005/6. Mowshowitz's dedication to teaching is very admirable, as she devotes all her time to her several hundred students and publishes papers on undergraduate education. That being said, her lectures are extremely repetitive and her notes are "organized" in a swirl of unnecessarily coordinated colors and prints that bring me back to kindergarten. The material she covers is interesting, of course, but her manner of presenting it kills its beauty. Her tests, however, are the most abominable part of this course - and not because they are conceptually challenging. Mowsh's questions are designed to trick you, which is not an inherently bad thing. The problem is that the only accepted answers are the ones she thinks as such. Even if you explain your logic in a perfectly sound manner, you do not get full credit (at least that was my experience). You have to teach yourself to look at what she wants you to know, biology notwithstanding. Never over-think the problem, and don't make too many logical assumptions. Instead make assumptions based on the material presented in class (for example, a seven-pass transmbrane protein will always be a GPCR, even if you have no experimental data to support that). To do well, do the problems and do them again. If you're premed, I pity you for having to take this course and I hope in the future Columbia's biology department will expand its repertoire of Intro bio professors. Columbia does a great disservice to its biology students by forcing them through a single introductory course fueled by one professor's well-intentioned but ineffective methodology and perpetuated by premed angst.