Just say no. This man cannot organize lectures, is not well versed in modern biology techniques and is not helpful inside or out of class. He seems like a very nice person, but I was completely disappointed in him as a lecturer. If you have to take Molecular Biology for the Biochemistry major (like me) - I wish you the best. Be prepared for ridiculous exams and painful lecture. If Molecular Biology is optional for you, steer clear.
I am writing this review hopefully in time before others chose this class - I was just made aware that Prywes didn't have a review. I wrote him a really, really, long CourseWorks review last semester - I wish I still had it saved somewhere!